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When Is The Best Time to Take Inositol for Weight Loss

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Inositol has been gaining popularity as a supplement for various health benefits, including weight loss. As more people seek natural and effective ways to manage their weight, understanding the optimal timing for taking inositol becomes crucial. 

This article delves into the science behind inositol, its role in weight management, and most importantly, the best times to consume this supplement to maximise its potential benefits. 

Whether you are looking to enhance your metabolism, reduce cravings, or improve insulin sensitivity, knowing when to take inositol can significantly impact your weight loss journey. The following insights take a look into the research and clinical recommendations to determine the most effective timing strategies for inositol supplementation.

Last Updated:
July 19, 2024
Paper written by:
Harriet Moxon, RN

Key Takeaways

  • Inositol enhances insulin sensitivity, which can aid in weight loss efforts.
  • It plays a significant role in maintaining metabolic and hormonal balance.
  • Inositol may assist in fat metabolism, appetite suppression, and reducing cravings.
  • Incorporating inositol into your daily routine can contribute to overall bodily harmony.
  • Inositol is particularly beneficial for individuals with PCOS, aiding in weight management.

Understanding Inositol and Its Role in Weight Loss

Inositol, sometimes referred to as vitamin B8, is a naturally occurring carbohydrate present in our bodies and various foods. The two primary forms found in supplements are myo-inositol (MI) and D-chiro inositol (DCI). 

Inositol is abundant in fruits, whole grains, nuts, beans, and organ meats, and our bodies can also produce it, primarily from glucose in the kidneys.

This sugar alcohol is essential for numerous bodily functions, including cell signalling, fat metabolism, and insulin sensitivity, all of which are crucial for weight management. Although not technically a vitamin, inositol functions similarly in many aspects, supporting overall health and well-being.

How Inositol Aids in Weight Loss

Inositol aids weight loss primarily by improving insulin sensitivity, allowing the body to utilise blood glucose more efficiently, which is crucial for shedding pounds. It also promotes fat metabolism, reducing the storage of excess fat. Additionally, inositol helps regulate appetite and decrease cravings, making it easier to adhere to a weight loss plan.

Inositol's role in maintaining cell health and signalling further supports weight loss. By ensuring proper cellular function and communication, inositol optimises the body’s overall metabolic processes, enhancing both weight management and general metabolic health.

Best Time to Take Inositol for Weight Loss

Optimising the timing of inositol intake can significantly enhance its effectiveness for weight loss. Here, we explore the best practices for when to take inositol to maximise its benefits.

Morning Intake

Taking inositol in the morning may offer several benefits. It helps regulate blood sugar levels and manage appetite throughout the day. This can be particularly helpful for those who struggle with mid-morning and afternoon cravings or have a tendency to overeat during the day. 

Inositol in the morning can also boost energy levels and improve focus, which can support a more active lifestyle, further aiding weight loss.

  • Regulates blood sugar levels
  • Reduces mid-morning and afternoon cravings
  • Enhances energy levels and focus

Evening Intake

Conversely, some individuals find that taking inositol in the evening supports better sleep and aligns with natural circadian rhythms. Quality sleep is crucial for metabolic health, and an evening dose of inositol might help reduce stress and improve overall sleep quality, which can indirectly aid weight management by promoting restorative sleep.

  • Supports better sleep quality
  • Reduces stress
  • Controls evening appetite and late-night snacking

Timing with Meals: Before or After Eating

Research indicates that the optimal time to take inositol is just before meals. This allows the body to absorb the supplement more effectively during digestion, enhancing its impact on insulin sensitivity, fat metabolism, and appetite control. 

For instance, taking inositol before breakfast can help stabilise blood sugar levels after the meal, reducing the likelihood of mid-morning energy crashes and unhealthy snacking. Similarly, taking it before dinner can help control evening appetite and reduce the tendency to snack late at night. 

While taking inositol after meals is still beneficial, it may not be as effective for weight loss as pre-meal consumption.

  • Enhances absorption during digestion
  • Improves insulin sensitivity and fat metabolism
  • Reduces the likelihood of unhealthy snacking

Frequency of Inositol Intake: Daily Dosage and Splits

For weight loss, the recommended daily dosage of inositol is typically 2 grams, divided into two doses of 1 gram each. This split dosage helps maintain consistent levels of inositol in the body throughout the day, thereby optimising its effects on metabolism and weight management. 

Taking 1 gram in the morning and another in the evening can ensure steady support for metabolic processes and appetite regulation.

  • Recommended daily dosage: 2 grams
  • Split into two doses of 1 gram each
  • Maintains consistent inositol levels throughout the day

Timing Breakdown

Timing of Inositol Intake

Potential Benefits

Potential Drawbacks

Morning

Regulates blood sugar and appetite throughout the day; beneficial for weight loss

May interfere with sleep for some individuals

Evening

Promotes better sleep and supports circadian rhythms

May not impact appetite and blood sugar regulation immediately

Before Meals

Enhances absorption and utilisation; supports insulin sensitivity and fat metabolism around mealtimes

Requires planning and consistency

After Meals

Beneficial for overall health and weight management

May not maximise weight loss benefits

Split Dosage (2 grams per day)

Maintains consistent inositol levels; optimises effects on metabolism and weight loss

Requires effort and consistency

To maximise the weight loss benefits of inositol, consider taking it in the morning to regulate appetite and blood sugar levels, or in the evening to support sleep and circadian rhythms. 

Taking inositol just before meals enhances its absorption and effectiveness, particularly in stabilising blood sugar and controlling appetite. Splitting the daily dosage into two equal parts—one in the morning and one in the evening—ensures consistent benefits throughout the day. 

Maximising the Benefits of Inositol

For optimal weight loss results with inositol, consider combining it with other supplements that enhance metabolic and hormonal health. Omega-3 fatty acids, vitamin D, and berberine are particularly effective choices. 

These supplements can work synergistically with inositol to improve insulin sensitivity, boost fat metabolism, and enhance overall well-being.

  • Omega-3 Fatty Acids: Found in fish oil or algae sources, omega-3s help reduce inflammation and support cardiovascular health.
  • Vitamin D: Essential for maintaining healthy hormone levels, which is crucial for metabolic and weight management.
  • Berberine: An herbal extract known for improving insulin function and glucose metabolism.

Pairing inositol with these complementary nutrients can amplify its weight loss benefits. For example, omega-3s from fish oil or algae sources can help reduce inflammation, while vitamin D supports healthy hormone levels. Berberine has been shown to improve insulin function and glucose metabolism, making it a powerful partner to inositol in supporting weight loss.

Before starting any new supplement regimen, it's essential to consult with a healthcare provider to determine the best combination for your specific needs and health goals.

Incorporating Inositol-Rich Foods

Besides taking inositol supplements, you can increase your intake by adding inositol-rich foods to your diet. Foods such as cantaloupe, oranges, kiwi, whole grains, nuts, beans, and organ meats are excellent sources of inositol. Including these foods in your diet can enhance your overall well-being and complement your supplementation routine.

  • Cantaloupe: A refreshing and hydrating fruit, rich in inositol.
  • Oranges: Provide a good dose of inositol along with vitamin C.
  • Kiwi: Packed with inositol and other essential nutrients.
  • Whole Grains: Such as brown rice and oats, which are high in inositol.
  • Nuts: Especially almonds and walnuts, offering a healthy snack option.
  • Beans: Legumes like lentils and chickpeas are great inositol sources.
  • Organ Meats: Liver and kidney, which are nutrient-dense and high in inositol.

Including these foods in your diet can enhance your overall well-being and work hand-in-hand with your supplementation routine.

Lifestyle Factors for Effective Weight Loss

To get the most out of inositol for weight loss, maintaining a healthy lifestyle is crucial. Regular exercise and a balanced, calorie-controlled diet are key components. Physical activity improves insulin sensitivity, boosts metabolism, and supports overall weight management. 

Pairing inositol with a nutritious, portion-controlled eating plan can create a powerful synergy, leading to more sustainable weight loss results.

  • Regular Exercise: Enhances insulin sensitivity and boosts metabolism.
  • Balanced Diet: Supports overall health and weight management.
  • Portion Control: Helps maintain a calorie deficit necessary for weight loss.

Research-Backed Benefits of Inositol for Weight Loss

Extensive scientific research has demonstrated the effectiveness of inositol supplementation in promoting weight loss, particularly in individuals who are overweight, obese, or have conditions like polycystic ovarian syndrome (PCOS). 

Studies have shown that taking 2 grams of myo-inositol twice daily can significantly decrease body mass index (BMI) and improve insulin sensitivity. Furthermore, research suggests that the timing of inositol consumption, such as taking it before meals, may enhance its benefits by affecting appetite and blood sugar regulation.

Key Studies and Findings

Several notable studies have provided valuable insights into the weight loss benefits of inositol. In a randomised, double-blind, placebo-controlled trial on the effects of myo-inositol on insulin resistance and lipid profile in PCOS patients, participants who took 2 grams of myo-inositol twice daily experienced a significant reduction in BMI and improved insulin sensitivity compared to the placebo group.

Another study on the effects of myo-inositol and D-chiro-inositol on metabolic parameters in PCOS patients found that a combination of myo-inositol and D-chiro-inositol (40:1 ratio) taken twice daily was more effective in reducing weight and improving metabolic markers than either supplement alone.

These studies highlight the potential of inositol in supporting weight loss, especially for individuals with weight management challenges or PCOS. The research also indicates that taking inositol before meals can enhance its weight loss benefits by improving appetite control and blood sugar regulation.

Potential Side Effects and Considerations

While inositol is generally well-tolerated, it's important to be aware of some potential side effects and considerations before incorporating it into your regimen. The good news is that inositol is considered safe by the FDA, with the designation of "generally recognised as safe" (GRAS).

Common Side Effects of Inositol

The most commonly reported side effects of inositol supplementation are mild and include nausea or stomach upset. These typically occur when taking high doses, usually above 4,000 mg per day. However, the majority of individuals tolerate inositol well, especially when starting with lower doses and gradually increasing as needed.

  • Nausea and Stomach Upset: These symptoms are usually mild and transient, often resolving as the body adjusts to the supplement. To minimise these effects, it is advisable to start with a lower dose and gradually increase it.
  • Diarrhoea: Some individuals may experience loose stools or diarrhoea, particularly at higher doses. Reducing the dose can help alleviate this side effect.
  • Headache: A small number of users have reported headaches when taking inositol. Staying hydrated and adjusting the dosage may help mitigate this issue.

Who Should Avoid Taking Inositol?

Although inositol is generally safe for most people, there are a few instances where caution is advised:

  • Severe Kidney or Liver Disease: Individuals with severe kidney or liver disease may need to avoid or adjust their inositol intake, as the body's ability to metabolise and excrete it may be impaired.
  • Pregnancy and Breastfeeding: While inositol is believed to be safe during pregnancy and breastfeeding, it is always best to consult with a healthcare provider before starting any new supplement.
  • Medications and Underlying Conditions: It's important to consult with a healthcare professional before starting inositol supplementation, especially if you have any underlying medical conditions or are currently taking medications, as interactions can occur.

If inositol isn't suitable for you, consider exploring alternative weight loss treatments. For example, our Super Fat Lipolysis service provides effective fat reduction.

Before you go...

With a solid understanding of how to optimise inositol for weight loss, consider exploring more about this supplement. Discover more articles to further your knowledge and continue your health journey with deeper insights into inositol and its benefits.

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Experience advanced laser science and innovative medical treatments. Book a consultation with Dr. Emanuel Paleco and his expert team at the Institute of Medical Physics. Contact us today to schedule your appointment and start your journey towards rejuvenation.

FAQs

What is inositol and how does it help with weight loss?

Inositol is a naturally occurring carbohydrate that plays a significant role in managing metabolic health and hormonal balance. It can aid in weight loss by improving insulin sensitivity, promoting fat metabolism, and helping to regulate appetite and cravings.

What is the recommended dosage of inositol for weight loss?

According to experts, the optimal dosage of inositol for weight loss is 2 grams taken twice daily, with the best time to take it being just before meals.

When is the best time to take inositol for weight loss - morning or evening?

Research suggests that taking inositol in the morning may be more beneficial for weight loss, as it can help regulate blood sugar and appetite throughout the day. However, the timing of inositol intake is ultimately a personal preference, and the most important factor is consistency in taking the supplement daily.

Are there any potential side effects or precautions to be aware of when taking inositol?

Inositol is generally well-tolerated, with occasional reports of mild side effects such as nausea or stomach upset, primarily from high doses (above 4,000 mg per day). However, it's important to consult with a healthcare professional before starting inositol supplementation, especially if you have any underlying medical conditions.

Can inositol help with weight loss for individuals with conditions like PCOS?

Yes, inositol has been shown to be particularly beneficial for individuals with polycystic ovarian syndrome (PCOS), as it can help manage insulin resistance and other metabolic factors that contribute to weight gain and difficulty losing weight.

Date First Published:
July 19, 2024
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By -

Harriet Moxon, RN

July 2, 2024

Institute of Medical Physics